![]() ![]() Furthermore, our data question the reliability of the Hemochron in assessing adequacy of heparin anticoagulation monitoring for CPB.ĪCT Activated clotting time Anticoagulation Cardiopulmonary bypass Heparin Method comparison Protamine. Methods: We performed parallel testing of the ACCRIVA Hemochron Signature Elite ACT+ and Hemochron Response analyzer, iSTAT platform, and 2 Hepcon Hemostasis Management System (HMS) Plus analyzers for monitoring intraoperative heparin treatment. ![]() Furthermore, while discrepancies in ACT between two parallel iSTAT assays showed little or no clinical relevance, deviations from parallel Hemochron assays and iSTAT versus Hemochron measurements revealed marked and sometimes clinically critical deviations.Ĭurrently used ACT point-of-care devices cannot be used interchangeably. Overall, disconcordant results according to clinically predefined target values were more frequent with the Hemochron than i-STAT. Although demonstrating a fair linear correlation (r = 0.815), parallel measurements on different ACT-devices showed large bias (-20s 95% LOA: - 290-250 s) and little concordance (kappa = 0.368). Hemochron derived ACTs demonstrated worse linear correlation (r = 0.782), larger bias with considerably broader LOA (- 13.14 s 95%LOA:-316.3-290 s), and lesser concordance between parallel assays (kappa = 0.554). The test sample and reagents never enter the ‘analyser’ which transforms electrical signals from the test cartridge into human-readable results. Bias, as determined by Bland-Altman analysis, was low (- 3.8 s 95% limits of agreement (LOA): - 77.8 -70.2 s), and Cohen's Kappa demonstrated good agreement (kappa = 0.809). The i-STAT is a cartridge-based analyser with all the analytical requirements for the performance of a test contained within an individual cartridge. From the ED to the physician’s office, clinical management decisions can be made immediately and result in improved patient safety, clinical outcomes, and overall patient satisfaction. Parallel i-STAT ACTs demonstrated a good linear correlation (r = 0.985). Point-of-Care Testing Designed to provide immediate, convenient, and easy-to-use diagnostic testing. Measurements were compared between identical and different device types using linear regression, Bland-Altman analyses, and calculation of Cohen's kappa coefficient. Blood samples from 30 patients undergoing cardiac surgery on CPB were assayed at specified steps (baseline, after heparin administration, after protamine administration) with four parallel measurements (two of each device type) using commercial Kaolin activated assays provided by the respective manufactures. We evaluated the agreement of ACT assays using four parallel measurements performed on two commonly used devices each (i.e., two Hemochron Signature Elite (Hemochron) and two Abbott i-STAT (i-STAT) devices, respectively). However, concerns exist regarding reproducibility of ACT assays and comparability of devices. Since inadequate heparin anticoagulation and insufficient reversal can result in complications during cardiopulmonary bypass (CPB) surgery, heparin anticoagulation monitoring by point-of-care (POC) activated clotting time (ACT) measurements is essential for CPB initiation, maintainance, and anticoagulant reversal. ![]()
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![]() ![]() What We Love: Sturdy construction, large capacity, versatile View On Amazon View On Walmart View On Bed Bath & Beyond The chamber easily detaches from the base, though I recommend washing by hand as a few user reviews state that the dishwasher damages some of the parts.ĭimensions (LxWxH): 10 x 12 x 19.25 inches | Material: Stainless steel | Capacity: 128 ounces | Power: 200 watts The cord stores away when you're done and it's also easy to clean. The blending case is double insulated to keep the drinks cold, and to keep the condensation away. Bonus points for weighing less than 11 pounds. You’ll need electricity to use it when you get to your destination, but getting there is easier than lugging around some of the much larger machines. It has a handle for easy carrying, and it’s smaller than most other models. Heading to a party after work? This margarita machine is easy to pack up and take on the go. What We Don’t Love: Parts are not dishwasher-safe What We Love: Handle for portability, easy to clean, large capacity It holds enough to make three jars’ worth of margaritas, which is approximately 108 ounces.ĭimensions (LxWxH): 9 x 14 x 19 inches | Material: Plastic | Capacity: 36 ounces | Power: 450 watts You don’t have to keep topping off the ice reservoir, though. It has a powerful wattage and can hold up to 36 ounces in the blender jar. "Simply add ice and your liquid ingredients, flip a switch, and you’ll be on your way to Margaritaville in minutes." "This machine provides perfect, uniform texture for frozen drinks of all kinds, and best of all, it’s incredibly easy to use," she says. For those who own a pool, I can imagine having one of these things running next to it all summer long." "This machine looks ideal for the home user," says Jeffrey Morgenthaler, a professional bartender with more than 25 years of experience and author of " The Bar Book: Elements of Cocktail Technique." "It's got a nice big ice reservoir, and I like the pre-programmed drink settings. Their Key West model is a great middle-of-the-road option that checks all the boxes without entering into commercial territory. Margaritaville offers multiple margarita machines that differ in terms of capacity, features, and price. What We Don’t Love: Plastic construction, ice may get jammed What We Love: Extra-large ice reservoir, 4 pre-programmed drink settings, dishwasher-safe parts View On Amazon View On Walmart View On Home Depot Whether it's for you or a party, here are the best margarita machines. I personally couldn’t turn down a frozen lemonade in the middle of summer. Margarita machines are also handy tools for making non-alcoholic frozen drinks like slushies. But when you want to quickly and easily whip up batch after batch of perfectly smooth drinks, a margarita machine is a game-changer." ![]() "Sure, a top-quality blender can make one or two frozen Margaritas or Pina Coladas. "If you love frozen drinks, and you also love to entertain, you need a margarita machine," says Amy Traynor of Moody Mixologist. A margarita machine takes homemade cocktails made with a shaker or blender to the next level, yielding the perfect slush consistency and icy temperature. With just a few simple ingredients and a fun countertop machine, you can impress your friends (and yourself) with restaurant-quality frozen margaritas. ![]() You don’t have to visit a bar or restaurant to enjoy one of these tropical cocktails, however. You can order a margarita straight up, on the rocks, or, what we're looking for here, frozen. It’s a simple drink made with tequila, lime juice, orange liqueur, and a rim of salt. A margarita is one of the most popular cocktails in the world. ![]() ![]() ![]() The system was sold with plastic overlays that were placed over the television screen to simulate graphics that the system was not capable of producing. Some of the add-on games did not include a game card but just new overlays and instructions that could be used with one of the game cards that came bundled with the system to give it a new functionality. Add-on games were sold individually for $5.49 or in a pack of 6 for $24.99. These jumpers merely unlocked onboard programming to play certain games and the cards themselves did not contain game data. The printed circuit board cards did not contain any components but had a series of jumpers between pins of the card connector. There was no power switch for the console as the system would turn on once a game was inserted into the system and turn off once the game was removed. The Odyssey used a type of removable printed circuit board card that inserts into a slot on the front of the system. ![]() In addition to the game cards and screen overlays the system came bundled with game accessories such as dice, scorecards, play money, casino chips and playing cards for each game. The 11 games that were bundled with the system were Analogic, Cat & Mouse, Football, Haunted House, Hockey, Roulette, Simon Says, Ski, States, Submarine and Tennis. The Odyssey system was powered by batteries, lacked any sound capability and was bundled with 2 controllers, 6 C batteries, 6 game cards which were capable of playing 11 games and 22 screen overlays (2 per game to support 2 different size television screens). By the time the system was released to the general public it was 4-year-old technology and the video arcade market was just gaining ground and had more advance technology. ![]() The system was a redesign of Ralph Baer’s “Brown Box” prototype which was completed in 1968. The Magnavox Odyssey was first demonstrated on and released in September 1972 with a price tag of $99.99. The first to be release was Magnavox Odyssey followed by Atari’s Pong home console and then the Coleco Telstar systems. The first generation of home consoles were made between 19 with three major companies competing to become the leader in the home video game market. This was the first home video game console and was the beginning of the home video game market which is now a multibillion-dollar industry. Their 1972 Odyssey home video game system, a production engineered version of the “ Brown Box” was the result. Two years later in 1971 Magnavox revisited the idea of television gaming and finally took a license from Sander Associates. The reactions were overwhelmingly favorable, but Magnavox did not want to take the risk involved in marketing the new concept to the general public and held off on moving forward. In 1969 representatives from Magnavox went to Sanders Associates in Nashua, New Hampshire where Ralph Baer and his team demonstrated Baer’s “Brown Box” prototype. ![]() ![]() ![]() ![]() usually present between the ages of 9 to 14 years ![]() this is the most common frx of the base of the 5th metatarsal hence, strictly speaking a Jones frx is an acute injury in addition, the acute Jones frx must be distinguished from the chronic Jones frx the later of which may represent a stress frx w/ poor prognosis for healing this fracture is usually proximal to the metatarsal cuboid joint Jones frx is located w/in 1.5 cm distal to tuberosity of 5th metatarsal & should not be confused w/ more common avulsion frx of 5 th metatarsal styloid It is important not to overlook other associated injuries to ligaments of the ankle and foot.- involves frx at base of fifth metatarsal at metaphyseal-diaphyseal junction, which typically extends into the 4-5 intermetatarsal facet In these cases, the bone fragments are repositioned and stabilized with screws and/or a plate. Surgery may be needed when there is complete displacement of the fracture fragments or failure to heal with non-operative treatment after several months. It can be many months before the bone is completely healed and a full recovery has been achieved. They can usually resume dance activities by 10-12 weeks and return to performance level by 19 weeks. Patients are often still symptomatic 6 to 8 weeks or more after this injury. This is a frustrating injury because it takes a long time for healing to occur. Usually by 6 weeks, there is enough healing to allow them to transition to a stiff-soled shoe with lots of padding. As the swelling settles and the fracture starts to heal, they can begin walking more extensively in the boot. Although weight bearing is allowed, for the first few weeks, they will have to significantly limit their walking and may need crutches due to pain and discomfort. Typically, patients are placed in a walking boot. Treatment involves relative rest and time to allow the fracture to heal. The fracture has a very high rate of healing with non-operative treatment. Figure 3A: X-ray from the side (Lateral View)Ī 5th metatarsal shaft “Dancer’s” fracture is an injury that is usually treated non-operatively. There will be gapping at the fracture and there may be some shortening or rotation of the fracture (Figures 3A-3B). The usual fracture pattern is a spiral running from the outside aspect of the bone (distal lateral) near the toes to the inside aspect of the bone near the ankle (proximal medial). The size of the fractured fragment may vary considerably. X-rays of the foot will reveal a long oblique fracture of the shaft of the 5th metatarsal. However, the main tenderness will usually be just before the base of the fifth toe. There may be tenderness and swelling over a large area of the outside of the foot. When pressing on the outside of the foot, there will be marked tenderness over the 5th metatarsal. Figure 2: Twisting mechanism causing injury It will be associated with quite specific local tenderness over the bone near the base of the fifth toe and on the outside of the foot (the 5th metatarsal). Over time, the skin can turn black and blue. Weight bearing on the injured foot may be difficult due to pain and discomfort. It can be associated with significant swelling. This will produce immediate pain over the outside aspect of the foot near the toes. An acute rolling of their ankle while pointing the toes down can also fracture the shaft of the 5th metatarsal (See Figure 1). Figure 1: 5th Metatarsal Shaft “Dancer’s” FractureĪ patient who suffers a 5 th shaft fracture (See Figure 1) commonly gives a history of a twisting injury to their ankle and foot (inversion and plantarflexion injury), similar to what occurs with an ankle sprain (Figure 2). However, since this fracture of the fifth metatarsal was first described in ballet dancer’s, it has become known as a dancer’s fracture as well. **There is another fracture that may also be referred to as a dancer’s fracture. It often takes 4 or more months for a full recovery to occur. It typically takes about 6 weeks for adequate bone healing to occur, before patients can start to significantly increase their activity level. In many instances, this type of fracture can be treated non-operatively, with relative immobilization in a walking boot combined with limited weight-bearing. This 5th metatarsal “Dancer’s” fracture causes localized pain, swelling, and difficulty walking. During this injury, the 5th metatarsal is twisted by a strong force resulting in a spiral fracture. A twisting injury to the ankle and foot may cause a long fracture of the 5th metatarsal shaft - the bone that attaches the little toe to the midfoot (Figure 1). ![]() ![]() ![]() So go ahead and download the PCSX2 BIOS now, and get started on enjoying some of your favorite PS2 games! Features of PCSX2 BIOS Stability while simulation That’s why we’ve gone ahead and provided a link to the most recent and safe BIOS file available, as well as a few tips on how to avoid any unwanted extras. The good news is that it’s easy to find and download the BIOS file the bad news is that it’s often bundled with other files and software that you may not want on your computer. In order to run the PCSX2 emulator, you need a PlayStation 2 BIOS image. Think of it like the operating system for your computer-without it, nothing would work. This file contains all of the information that the emulator needs in order to function, and without it, you won’t be able to play any PS2 games. ![]() ![]() The BIOS is a file that’s required in order for the PCSX2 emulator to run. In this blog post, I’ll show you how to find and download the PCSX2 BIOS-the most popular PS2 emulator-as well as walk you through the basic steps of setting it up and getting started. Luckily for us gamers, many of those classics are now available for download on modern platforms thanks to emulator software. You remember the hours spent grinding away in Final Fantasy X, mastering all of the Dragon Quest characters in their best outfits, or unlocking everything God of War had to offer. If you’re like me, you grew up playing the classics on your Playstation. ![]() ![]() ![]() Once you enable the Unknown source, then you are good to go to install and play the game.If it’s not installed, make sure to enable the “Unknown Source” option in Privacy settings.After downloading the apk file, simply install the game. ![]() Step3 Install PUBGMobile Lite and allow your device to install unknown resources from the web. Step2 Search PUBGMobile Lite and tap on the most prominent option. This includes bug fixes, performance and stability improvements, visual enhancements, and much more. A Step-By-Step guide on How to Download PUBG Mobile Lite without VPN. If you are facing any issue to download the game from PlayStore then download the updated version from here. Download PUBG Mobile Lite 0.25.0 APK and OBB Files The PUBG Mobile Lite 0.25.0 update is finally here, and it has arrived filled to the brim with exciting new content and features.Upgraded buggy with machine guns, and also can float in water.On the other hand, the global version of PUBG Mobile just recently updated to v1.6.0 alongside the Battlegrounds Mobile India 1.6 update exclusive to India. So download PUBG Mobile Lite 0.22.0 APK and OBB files from below. Armored Jeep with upgraded machine guns. The PUBG Mobile Lite Play Store listing has been updated featuring new build 0.22.0 dated September 23, 2021.New helicopter with army skin (could be found near a warehouse in Stronghold).A new area in payload 2.0 named Stronghold.Pubg Mobile Lite Beta update Payload 2.0 Features But as we all know that Pubg Lite is the lighter version of Pubg Mobile, so for those users, the Payload 2.0 is available. Recently Pubg Mobile Payload 2.0 has also arrived with some great new features. So in the case of Payload 2.0 in Pubg lite we gonna see further beta updates very soon.Īs the first beta is already available, featuring a new location known as Stronghold. Adding new features to the game require up to 4 Beta updates. As this is not the final update to the game, it means the developers will add more beta version in the coming weeks. Pubg Mobile Lite update payload 2.0 mode has recently arrived in the beta version. ![]() ![]() And although it didn’t result in the two getting back together, they continue to co-parent their two daughters, Georgie and Katie, as a cohesive parenting unit. However, this step actually kind of brought the two closer together. It officially confirmed that they are in fact divorced now. This storyline started in Heartland season 8 and dragged all through season 9, with them dealing with the separation, telling their daughters about it and finally deciding to divorce.īut only on season 10 episode 10 Lou and Peter actually sign divorce papers. Do they divorce? Or do they get back together? So I thought I start this questions and answers post with that.Īnd, unfortunately, there isn’t a happy answer to this question, because, yes, Lou and Peter do get a divorce. One of the most popular questions out there is what happened to Lou and Peter in Heartland. Do Heartland’s Lou and Peter get a divorce on the show? ![]() Especially if you haven’t seen all of the show’s seasons. This is why I thought I should do a blog post answering some of the most popular Heartland questions, so you have the answers all in one place.įair warning though, this post does contain Heartland spoilers, so keep that in mind. They range from what happens to Lou and Peter to questions about Mallory as well as inquiries about Ty’s faith on Heartland season 10. ![]() ![]() When it comes to CBC’s Heartland, there have been many questions the fans of the show have been asking over the course of the seasons. We may earn a small commission from qualifying purchases. ![]() ![]() However, again, at time of writing there is no way to play Dying Light 2 crossplay and over different platforms. JanuIs Dying Light Cross Platform in 2023 Find out if Dying Light is cross-platform (crossplay) across PS4, Xbox One, Steam, Windows, PS5, XBox Series S/X, Switch, iOS & Android here. The 2019 reboot of Infinity Wards iconic FPS game is. ![]() Is Dying Light crossplay PS4 and PC At this time, Dying Light is not crossplay compatible with. Unfortunately, general cross-platform gameplay or save transfer is not possible for DYING LIGHT. Considering Dying Light 2 "guarantees to expand the world for at least five years post-launch", we know that updates and changes to the game are scheduled for a long time to come, though their content is still unclear. Yes, Call of Duty: Modern Warfare is a cross-platform game with support for cross-platform play. No, Dying Light is not cross-platform between Xbox 2 and PS4. Modified on: Wed, 2 Mar, 2022 at 10:13 AM - There are a lot of pages that say DL has crossplay and yet it doesnt work - Stop reading the pages that say so, please. Dying Light 2 released earlier this month, but that doesnt mean the first game of zombie-parkour-survival no longer has value. The reality is that while it has not been promised, nor have the official comments from Techland ruled it out yet. ![]() ![]() ![]() The LEDs will die.īut how do you control the electricity passing through the devices? You need a resistor. You don’t want to expose LEDs to excess power. If you want to know where the resistor goes, you must first figure out what the resistor does. ![]() ![]() The current flows from the positive to the negative. Instead, they will say ‘Anode’ to refer to the positive side and ‘Cathode’ to refer to the negative side.īut the concept is the same. The average technician won’t use the terms ‘Positive’ or ‘Negative’ to describe an LED’s polarity. Some of the experts you consult regarding the possibility of connecting the resistor to the positive or negative side may reject your question altogether because LEDs don’t have positive or negative sides.īut that is not entirely true. You don’t have to worry about destroying the LED because you wired the device poorly. This sounds annoying, but it is a good thing. Therefore, if you wire an LED backward, it won’t work. Electricity will flow through the LED in one direction, which is why polarity is so important. The current will flow through the resistor regardless of the direction. You don’t have to connect the resistor in a particular configuration for the device to perform its role. Therefore, even if you connect them backward, they will work. Resistors are unaware of a circuit’s polarity. However, the polarity doesn’t matter to the operations of the resistor. LEDs require a resistor because they don’t have enough internal resistance. Resistor On Positive Or Negative Side Of Led This guide will give you a definitive answer. Should you place the resistor on the positive or negative side of the LED? Despite what some people say, you don’t have to guess. How true is this? Does it apply to LEDs? LEDs have polarities. But the resistor doesn’t care whether the connected leg is positive or negative. The current is supposed to enter through the positive side. ![]() ![]() Since their breakaway from the Citroën brand in 2015, DS has established itself as a producer of top-quality, luxury cars, and the DS 7 CROSSBACKlives up to this reputation. Search New Hyundai Kona Search Used Hyundai Kona DS 7 CROSSBACK There's also the impressive Kona electric, which offers an all-electric range of up to 300miles and a 0 to 62mph time of just 7.9 seconds. This system allows the Kona to achieve up to 57.6mpg WLTP combined. The most frugal is the hybrid powertrain, which combines a 1.6-litre diesel engine with an electric motor to produce a total power output of 141bhp. Hyundai have implemented a number of intelligent powertrains to ensure it's both engaging to drive and economical. Better yet, Hyundai's 5-year unlimited mileage warranty means that your Kona may be covered for a significant amount of time. The Konais a compact SUV that possesses a distinctive exterior design and a multitude of advanced technology, making it a popular choice for drivers. If you're not too fussed about speed and want the most cost-effective C-HR available then you'll find the 120bhp 1.8-litre petrol hybrid the most attractive option, achieving up to 57mpg.Ī traditional petrol-powered internal combustion engine is available, but time spent refueling may be more frequent than its hybrid counterparts due to fuel economy figures of around 44mpg. Models with this powertrain can go from 0 to 62mph in as little as 8.2 seconds whilst still offering fuel economy figures of up to 53mpg. The most fun will be had behind the wheel of the 2.0-litre 181bhp petrol hybrid. There are a few powertrains to choose from, but for maximum economy you'll want one of the hybrid powertrains. One of the sportier-looking SUVs on this list, the Toyota C-HR offers an enjoyable driving experience as well as decent levels of practicality. ![]() Four-wheel drive models are also available within the range, but this reduces economy slightly. The petrol engines aren't too far away from their diesel counterparts in terms of efficiency all petrol variants are capable of achieving around 54mpg. More potent diesel engines are available (150bhp and 190bhp), but bear in mind that the more powerful you go, the more expensive it costs to run. Search New Peugeot 3008 Search Used Peugeot 3008 Skoda KaroqĬoming with top levels of practicality and a great value for money proposition, the Skoda Karoq is the Czech manufacturer's offering within the competitive mid-sized SUV space.Īs expected (due to the lack of a hybrid), the Karoq's diesel engines are the most efficient, with the 115bhp 1.6-litre TDI achieving up to 63mpg. If you're not quite convinced by hybrid technology and want something more traditional, the 1.5-litre diesel and 1.2-litre petrolare worth looking at, offering around 57mpg and 47mpg respectively. The most efficient is the 1.6-litre plug-in hybridwhich comes with either 225bhp or 300bhp and can achieve upwards of 200mpg and an all-electric driving range of up to 40 miles when the batteries are fully charged. There are a variety of powertrains to choose from, each highly economical in their own right. This mid-sized family SUV offers plenty of elegance and kerb appeal, as well as advanced technology and a good level of versatility. Looking for something with a bit of French flair? The Peugeot 3008 may be just the ticket. Search New Ford Puma Search Used Ford Puma Peugeot 3008 0 to 62mph will take 9.8 seconds (124bhp) or 8.9 seconds (153bhp), but if you're willing to sacrifice a bit on fuel economy, the ST version can complete the same sprint in 6.7 seconds whilst still offering around 40mpg. ![]() The intelligent 1.0-litre mild hybrid EcoBoost powertrain is the main reason why the Puma has made this list, offering fuel economy figures of around 50mpg on a combined cycle in both 124bhp and 153bhp forms.įord haven't forgotten the driving experience either, ensuring the Puma is both great fun to drive and highly economical. Don't let the word compact fool you though, as the Puma still offers plenty of the usual SUV traits such as a large boot and a spacious interior. The Puma nameplate was reintroduced into the Ford range in 2019, this time coming in a sleek compact SUV guise that caught the attention of many. With a wide range of both new and used options available on the market, we take a look at some of the most economical SUVs to assist in your search for your next car. Some SUVs are even ULEZ compliant, meaning you'll avoid charges when entering these zones. ![]() The SUVs we know and love today are a long way away from the gas-guzzling SUV behemoths of yesteryear thanks to developments in powertrain technology, making SUVs cleaner and more economical to drive. Often offering a comfortable ride, enhanced practicality and great all-round capabilities, the SUV has become the go-to car for many around the UK. ![]() |
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